DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and ...
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The accurate replication of DNA is important in the maintenance of the genetic integrity of an organism, and DNA polymerases have biochemical mechanisms to copy ...
Jun 6, 2019 · (2005) DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base ...
Jun 4, 2009 · Base propenals and malondialdehyde react with DNA to form adducts, including 3-(2′-deoxy-β-d-erythro-pentofuranosyl)pyrimido[1,2-α]purin-10(3H)- ...
DNA: Replication, Repair, and Recombination. Sulfolobus solfataricus DNA Polymerase Dpo4 Is Partially Inhibited by “Wobble” Pairing between O6-Methylguanine and ...
Missing: Ethenoguanine-
Jan 29, 2004 · Dpo4 binds DNA with an affinity similar to that of replicative polymerases due to the presence of an atypical little finger domain and a highly ...
We examined the effect of a single O6-methylguanine (O6-. MeG) template residue on catalysis by a model Y family poly- merase, Dpo4 from Sulfolobus ...
... DNA polymerases. However, hpol κ can efficiently bypass DNA-peptide cross-links if the peptide is N-substituted and linked to the N2 position of G, which ...
Solfataricus, a DinB-like Y family polymerase, efficiently replicates DNA past an abasic lesion. We have determined crystal structures of Dpo4 complexed with ...
Jan 27, 2009 · PubMed Abstract: In contrast to replicative DNA polymerases, Sulfolobus solfataricus Dpo4 showed a limited decrease in catalytic efficiency (k( ...